Short uses : F-Pree-GAH-ba-lin: used to treat pain caused by nerve damage due to diabetes and shingles (herpes zoster) infection.
It is also used with other medications to treat certain types of seizures (partial onset seizures).Use this medication regularly in order to get the most benefit from it. This drug works best when the amount of medicine in your body is kept at a constant level. Therefore it is best to take pregabalin at evenly spaced intervals throughout the day and night.
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DRUG CLASS AND MECHANISM: Pregabalin is an oral medication that is
chemically related to gabapentin. It is used for treating pain caused
by neurologic diseases such as neuropathic pain, postherpetic neuralgia
as well as seizures. The mechanism of action of pregabalin is unknown.
Pregabalin binds to calcium channels on nerves and may modify the release
of neurotransmitters that nerves use to communicate with each other.
Reducing communication between nerves may contribute to pregabalin’s
effect on pain and seizures. Pregabalin was approved by the FDA in
June, 2005.
Pregabalin should be stored at room temperature, between
15-30°C (59-86°F).
PRESCRIBED FOR:
Pregabalin is used for neuropathic pain associated
with diabetic peripheral neuropathy; postherpetic neuralgia; and
in combination with other drugs to treat partial onset seizures in
adults.
DOSING:
Pregabalin may be administered with or without food. The initial
dose for neuropathic pain is 50 mg three times a day (150 mg/d).
The dose may be increased to a maximum dose of 100 mg 3 times daily
(300
mg/d) after one week.
The recommended starting dose for postherpetic neuralgia is
