Brand name:

ASTIN (Atorvastatin, Lipitor)
Pronounced: LIP-ih-tor
Generic name: Atorvastatin calcium
Why is Astin prescribed?

Astin is a cholesterol-lowering drug. Your doctor may prescribe it along with a special diet if your blood cholesterol or triglyceride level is high and you have been unable to lower your readings by diet alone. The drug works by helping to clear harmful low-density lipoprotein (LDL) cholesterol out of the blood and by limiting the body's ability to form new LDL cholesterol.

Your doctor may prescribe Astin to reduce your chances of having a heart attack or developing heart disease if you have any of the following risk factors:

* Are age 55 years or older
* Smoke
* Have high blood pressure
* Have low levels of HDL (high-density lipoprotein--the good cholesterol)
* Have a family history of early heart disease

For people at high risk of heart disease, the doctor may suggest a cholesterol-lowering medication if LDL readings are 130 or more. For those at low risk, a medication is considered at readings of 190 or more.
Most important fact about Astin

Astin is usually prescribed only if diet, exercise, and weight loss fail to bring your cholesterol levels under control. It's important to remember that Astin is a supplement--not a substitute--for those other measures. To get the full benefit of the medication, you need to stick to the diet and exercise program prescribed by your doctor. All these efforts to keep your cholesterol levels normal are important because they may lower your risk of heart disease.
How should you take Astin?

Astin should be taken once a day, with or without food. You can take it in the morning or the evening, but should hold to the same time each day. The drug generally begins working within 2 weeks.

For an even greater cholesterol-lowering effect, your doctor may prescribe Astin along with a different kind of lipid-lowering drug such as Questran or Colestid. It's important to avoid taking the two drugs at the same time of day. Take Astin at least 1 hour before or 4 hours after the other drug.

Why should Astin not be prescribed?

Never take Astin during pregnancy or while breastfeeding. You should also avoid Astin if you have liver disease, or if the drug gives you an allergic reaction.
Special warnings about Astin

There is a slight chance of liver damage from Astin, so your doctor may order a blood test to check your liver function before you start taking the drug, again 12 weeks after you begin therapy or your dosage is increased, and periodically thereafter. If the tests reveal a problem, you may have to stop using the drug.

Drugs like Astin have occasionally been known to damage muscle tissue, so be sure to tell your doctor immediately if you notice any unexplained muscle tenderness, weakness, or pain, especially if you also have a fever or feel sick. Your doctor may want to do a blood test to check for signs of muscle damage.

If you are scheduled for major surgery, your doctor will have you stop taking Astin a few days before the operation.
Possible food and drug interactions when taking Astin

If you take Astin with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Astin with any of the following:

Antacids such as Maalox TC Suspension
Clofibrate (Atromid-S)
Colestipol (Colestid)
Cyclosporine (Sandimmune, Neoral)
Digoxin (Lanoxin)
Drugs that suppress the immune system
Erythromycin (E.E.S., Erythrocin, others)
Fenofibrate (Tricor)
Fluconazole (Diflucan)
Gemfibrozil (Lopid)
Itraconazole (Sporanox)
Ketoconazole (Nizoral)
Niacin (Niaspan, Niacor, Slo-Niacin)
Oral contraceptives
Special information if you are pregnant or breastfeeding

Developing babies need plenty of cholesterol, so this cholesterol-lowering drug should never be used during pregnancy. In fact, your doctor is unlikely to prescribe Astin if there is even a chance that you may become pregnant. If you do conceive while taking Astin, notify your doctor right away. Astin does make its way into breast milk, so you should not take the drug while breastfeeding your baby.
Recommended dosage for Astin

You need to follow a standard cholesterol-lowering diet before starting Astin, and should continue following it throughout your therapy.

ADULTS/ Overdosage

Although no specific information about Astin overdose is available, any medication taken in excess can have serious consequences. If you suspect an overdose of Astin, seek medical attention.

If you miss a dose...

Take the forgotten dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.

Storage instructions...

Store at room temperature.
Astin side effects

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Astin.

* Side effects may include:
Abdominal pain, abnormal heartbeat, accidental injury, allergic reaction, arthritis, back pain, bronchitis, chest pain, constipation, diarrhea, dizziness, flu symptoms, fluid retention, gas, headache, indigestion, infection, inflammation of sinus and nasal passages, insomnia, joint pain, muscle aching or weakness, nausea, rash, stomach pain, urinary tract infection, weakness