Brand name: RIBAVIN (Ribavirin, Rebetol)
Pronounced: REB-eh-tol
Generic name: Ribavirin
Why is RIBAVIN (Ribavirin, Rebetol) prescribed?

In combination with the interferon drugs Intron A or PEG-Intron, RIBAVIN (Ribavirin, Rebetol) is prescribed to treat chronic hepatitis C. RIBAVIN (Ribavirin, Rebetol) is always used with one of the other drugs. By itself, it is ineffective against hepatitis C.
Most important fact about RIBAVIN (Ribavirin, Rebetol) WITHOUT prescriptions

Extreme care should be taken to avoid pregnancy when a woman or her partner is taking RIBAVIN (Ribavirin, Rebetol). The drug poses a significant risk of serious harm to developing infants, even at lower doses, and it can also cause abnormalities in a man's sperm. The doctor will want to see a negative pregnancy report immediately before starting RIBAVIN (Ribavirin, Rebetol) therapy; and pregnancy tests should be done every month during therapy and for six months after it stops. Use at least two forms of birth control during treatment and for six months afterwards.
How should you take RIBAVIN (Ribavirin, Rebetol)?

RIBAVIN (Ribavirin, Rebetol) is available in capsule and oral solution forms. Make sure you drink plenty of water while taking RIBAVIN (Ribavirin, Rebetol), especially when you first begin taking RIBAVIN (Ribavirin, Rebetol). RIBAVIN (Ribavirin, Rebetol) may be taken with or without food when used in combination therapy with Intron A, but whichever way you choose, do it consistently. When RIBAVIN (Ribavirin, Rebetol) is used in combination therapy with PEG-Intron, the manufacturer recommends taking the dose with food.

If you miss a dose...

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.

Storage instructions...

Store at room temperature.
RIBAVIN (Ribavirin, Rebetol) side effects

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor immediately. Only your doctor can determine whether it is safe for you to continue taking RIBAVIN (Ribavirin, Rebetol).

* Side effects may include:
Anemia, blood disorder, depression, fatigue, fever, hair loss, headache, insomnia, irritability, joint or muscle pain, nausea, shortness of breath, weight loss

Why should RIBAVIN (Ribavirin, Rebetol) not be prescribed?

Do not take RIBAVIN (Ribavirin, Rebetol) if:

You are pregnant or your partner is pregnant
You have autoimmune hepatitis (RIBAVIN (Ribavirin, Rebetol) can make this type of hepatitis worse.)
You have certain blood disorders, such as thalassemia major or sickle-cell anemia
You have severe or unstable heart disease
You've ever had an allergic reaction to the active ingredient ribavirin
Special warnings about RIBAVIN (Ribavirin, Rebetol)

Within two weeks of starting treatment with RIBAVIN (Ribavirin, Rebetol), about one patient in 10 develops a severe form of anemia. Your doctor will order blood tests periodically to check for this condition. Severe anemia is a serious condition that can lead to a potentially fatal heart attack. RIBAVIN (Ribavirin, Rebetol) should be used with caution if you have a heart condition. Your doctor will perform heart tests such as an ECG before you begin treatment and will monitor your heart closely while you are taking RIBAVIN (Ribavirin, Rebetol). You may have to discontinue therapy if you develop heart-related problems or if your heart condition gets worse.

Treatment with RIBAVIN (Ribavirin, Rebetol) and Intron A or PEG-Intron can have other serious side effects, including depression and suicidal thoughts (especially in adolescents), changes in bone marrow, pancreas and lung disorders, diabetes, and immune and infectious disorders. If you develop symptoms of these conditions, your doctor may have to discontinue treatment with RIBAVIN (Ribavirin, Rebetol).

The risk of side effects is greater for individuals with poor kidney function. If you have this problem, your doctor will monitor you closely and adjust your dosage if necessary. Since many older adults have impaired kidney, liver, and heart function, the dosage of RIBAVIN (Ribavirin, Rebetol) is often decreased for these individuals.

The safety and effectiveness of RIBAVIN (Ribavirin, Rebetol) treatment have not been established for individuals with organ transplants, uncontrolled liver disease, and hepatitis B or HIV infections. Your doctor will have your liver function tested before you begin taking RIBAVIN (Ribavirin, Rebetol).
Possible food and drug interactions when taking RIBAVIN (Ribavirin, Rebetol)

If RIBAVIN (Ribavirin, Rebetol) is taken with other drugs, the effects of either could be increased, decreased, or altered. Check with your doctor before combining RIBAVIN (Ribavirin, Rebetol) with other medications.
Special information if you are pregnant or breastfeeding

RIBAVIN (Ribavirin, Rebetol) may cause birth defects or death in the developing infant. Neither a woman nor her partner should take RIBAVIN (Ribavirin, Rebetol) while she is pregnant. Use two forms of contraception if either partner is taking RIBAVIN (Ribavirin, Rebetol). Continue using two forms of contraception for 6 months after treatment is finished. If pregnancy occurs during RIBAVIN (Ribavirin, Rebetol) therapy or within 6 months afterwards, check with your doctor immediately.

It is not known whether RIBAVIN (Ribavirin, Rebetol) appears in breast milk. Because of the potential for serious adverse effects on the nursing infant, you should not breastfeed your baby while taking RIBAVIN (Ribavirin, Rebetol).
Recommended dosage for RIBAVIN (Ribavirin, Rebetol)

Your doctor will tailor your dosage to fit your needs. Your dosage will be lowered if you develop anemia while taking RIBAVIN (Ribavirin, Rebetol).

TREATMENT WITH RIBAVIN (Ribavirin, Rebetol) AND INTRON A
Overdosage

No adverse effects of RIBAVIN (Ribavirin, Rebetol) overdose have been reported. Nevertheless, any medication taken in excess may have serious consequences. If you suspect an overdose of RIBAVIN (Ribavirin, Rebetol), seek medical attention immediately.